RESEARCH

At TCU, Dr. Watts directs the Laryngeal Function Laboratory, which serves as the research arm of Endeavor Parkinsonology. Dr. Watts’ research is committed to creating new knowledge through research to improve how we assess and treat voice and swallowing impairments experienced by people with PD.

Dr. Watts is currently seeking people with PD to volunteer as participants in his research. If you have an interest in helping Endeavor Parkinsonology discover ways to fight against PD through research, please contact Dr. Watts at c.watts@tcu.edu.

RESEARCH VOLUNTEER OPPORTUNITY: We are investigating how Parkinson’s disease effects voice and swallowing. (TCU IRB#2022-205). Changes to voice and swallowing are common in PD but factors related to how they change over time are not well understood. Our aim is to measure voice and swallowing function and determine what factors are associated with changes that are different from normal aging. We are recruiting volunteers with PD and those without PD so that we can compare Parkinson’s with aging. For more information about volunteering please contact Dr. Watts at c.watts@tcu.edu.

RESEARCH VOLUNTEER OPPORTUNIY: We are investigating the effects of unique swallowing exercise program on the safety of swallowing in People with Parkinson’s disease (TCU IRB#2024-202). This is a clinical intervention study where participants will complete clinician-guided swallowing exercises over a six week period. Our aim is to determine if people with PD who have changes to laryngeal closure speed during swallowing (e.g., difficulty getting food or liquid down) can improve swallowing safety through this exercise program. For more information about volunteering please contact Dr. Watts at c.watts@tcu.edu.

RESEARCH VOLUNTEER OPPORTUNITY: We are investigating the effects of physical activity on inflammation in Parkinson’s Disease (TCU IRB#2024-59). Neuroinflammation is one of the theories attempting to explain the onset and progression of PD. Our aim is to investigate how levels of physical activity (“exercise”) influence inflammation in the body by measuring levels of an anti-inflammatory protein called Clusterin, which we are able to measure in blood samples. We are recruiting volunteers regardless of your activity level. For more information about volunteering please contact Kailie McGee at Kailie.mcgee@tcu.edu.

PARKINSONOLOGY RESEARCH

The overarching goal of this line of research is to expand human knowledge of how Parkinson’s disease (PD) effects laryngeal function in voice and swallowing to inform the development of more effective treatments to rehabilitate and/or sustain those functions. We are specifically interested in how voice and swallowing impairments manifest in different clinical phenotypes (e.g., subtypes) of PD. Our research investigates how voice and swallowing are influenced by PD tremor phenotype (e.g., tremor dominant vs. non-tremor dominant), age of onset (e.g., late onset vs. younger onset), sex, and years post-onset. A major aim of this research is to increase our understanding of how and why laryngeal function in voice and swallowing is impaired heterogeneously (differently) across the large population of people with PD.

PARKINSONOLOGY PUBLICATIONS BY DR. WATTS

Watts CR, Thijs Z, King A, Carr JC, Porter R. (2023). A pilot study of the effect of a non-contact boxing exercise intervention on respiratory pressure and phonation aerodynamics in people with Parkinson’s disease. Journal of Clinical Medicine. https://pubmed.ncbi.nlm.nih.gov/37510921/

Thijs Z, Zhang Y, Van Lierde K, Vanryckeghem M, Watts CR (2023). Self-perceived affective, behavioral, and cognitive reactions associated with voice use in people with Parkinson’s disease: A pilot study. Logopedics Phoniatrics Vocology. https://pubmed.ncbi.nlm.nih.gov/35695084/

Dumican M, Watts CR, Drulia T, Zhang Y. (2023). Dysphagia presentation, airway invasion, and gender differences in a clinically based sample of people with Parkinson’s disease. Dysphagia, 38(1):353-366. https://pubmed.ncbi.nlm.nih.gov/35809095/

Watts CR, Zhang Y (2022). Progression of Self-Perceived Speech and Swallowing Impairment in Early-Stage Parkinson’s Disease: Longitudinal Analysis of the Unified Parkinson’s Disease Rating Scale. Journal of Speech, Language, Hearing Research, 65(1): 146-158. https://pubmed.ncbi.nlm.nih.gov/34851686/

Thijs Z, Watts CR (2022). Perceptual Characterization of Voice Quality in Non-Advanced Stages of Parkinson’s Disease. Journal of Voice,6(2): 293.e11−293.e18 https://pubmed.ncbi.nlm.nih.gov/32703725/

Dumican M, Watts CR (2022). Swallow Safety and Laryngeal Kinematics: A Comparison of Dysphagia between Parkinson’s Disease and Cerebrovascular Accident. Journal of Parkinson’s disease,2022;12(7):2147-2159. https://pubmed.ncbi.nlm.nih.gov/36120789/

Thijs Z, Zhang Y, Van Lierde K, Vanryckeghem M, Watts CR (2022). Partner Perception of Affective, Behavioral, and Cognitive Reactions to Voice Use in People with Parkinson’s Disease. Clinical Parkinsonism & Related Disorders, 9(7) https://pubmed.ncbi.nlm.nih.gov/35860426/

Kim J, Watts CR (2021). A Comparison of Swallow-Related Submandibular Contraction Amplitude and Duration in People with Parkinson’s Disease and Healthy Controls. International Journal of Speech-Language Pathology. https://pubmed.ncbi.nlm.nih.gov/32466679/

Panzone L, Watts CR. (2020). Regulation of Transglottal Airflow in Speakers with Parkinson’s Disease. Journal of Voice, 34 (6): 961.e1-961.e7. https://www.ncbi.nlm.nih.gov/pubmed/31350111

Dumican M, Watts CR (2020). Predicting Airway Invasion Using Screening Tools and Laryngeal Kinematics in People with Parkinson’s Disease: A Pilot Study. Journal of Parkinson’s Disease. https://pubmed.ncbi.nlm.nih.gov/32538868/

Burk B, Watts CR (2019). The Effect of Parkinson’s Disease Tremor Phenotype on Cepstral Peak Prominence and Transglottal Airflow in Vowels and Speech. Journal of Voice, 33(4): 580.e11-580.e19.
https://www.ncbi.nlm.nih.gov/pubmed/29472149

Watts CR (2016). A Retrospective Study of Long-Term Treatment Outcomes for Reduced Vocal Intensity in Hypokinetic Dysarthria. BMC Ear, Nose, and Throat Disorders. 16:2. eCollection doi: 10.1186/s12901-016-0022-8.
https://www.ncbi.nlm.nih.gov/pubmed/26839511

Rousseau B, Watts CR. (2002). Susceptibility of speakers with Parkinson disease to delayed auditory feedback. Journal of Medical Speech-Language Pathology, 10(1): 41-49.
https://www.researchgate.net/profile/Christopher_Watts3

Watts CR, VanRyckeghem M. (2001). Laryngeal dysfunction in Amyotrophic Lateral Sclerosis. BMC Ear, Nose, and Throat Disorders, (1).
https://www.ncbi.nlm.nih.gov/pubmed/11722802

Watts CR, Dagenais P. (2001). Effects of attentional load on speech rate reduction in subgroups of speakers with Parkinson’s disease. Journal of Medical Speech-Language Pathology, 9(1): 55-61.
https://www.researchgate.net/profile/Christopher_Watts3